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High Potential of Bacterial Adhesion on Block Bone Graft Materials

Themistoklis Nisyrios, Lamprini Karygianni, Tobias Fretwurst, Katja Nelson, Elmar Hellwig, Rainer Schmelzeisen, Ali Al-Ahmad Bone graft infections represent a challenge in daily clinics, resulting in increased patient discomfort and graft removal. The aim of this study was to investigate the initial adhesion of five representative pathogens on three different block bone graft materials (xenogeneic, alloplastic […]

Integrity of dural closure after autologous platelet rich fibrin augmentation: an in vitro study

I Vasilikos, J Beck, S Ghanaati, J Grauvogel, T Nisyrios, K Grapatsas, U Hubbe Background: Watertight closure of the dura mater is fundamental in neurosurgery. Besides the classical suturing techniques, a variety of biomaterials have been proposed as sealants. Platelet rich fibrin (PRF) is an autologous biomaterial which can readily be obtained through low-speed centrifugation of […]

Effect of thrombosis-related gene polymorphisms upon oral cancer: a regression analysis

Antonis Vylliotis, Christos Yapijakis, Emeka Nkenke, Themistoklis Nisyrios, Dimitrios Avgoustidis, Maria Adamopoulou, Vasilios Ragos, Stavros Vassiliou, Nikolas Koronellos, Eleftherios Vairaktaris It is well-known that there is an interplay between hemostasis, thrombosis and cancer. Functional DNA polymorphisms in genes encoding factors related to thrombosis have been associated with increased risk for oral squamous cell carcinoma (OSCC). […]

Prevalence of human papillomavirus in saliva and cervix of sexually active women

Maria Adamopoulou, Eleftherios Vairaktaris, Emeka Nkenke, Dimitrios Avgoustidis, Petros Karakitsos, Vasilios Sioulas, Themistoklis Nisyrios, Christos Yapijakis Objective: Human papillomavirus (HPV) is strongly associated with cervical cancer and possibly with some oropharyngeal cancers. However, the relation between oral and cervical HPV infection is not fully understood. This study evaluates the prevalence rate and type-concordance of HPVs in […]

Oral carcinogenesis is not achieved in different carcinogen-treated PAI-1 transgenic and wild-type mouse models

Dimitris Avgoustidis, Themistoklis Nisyrios, Emeka Nkenke, Roger Lijnen, Vassilis Ragos, Despina Perrea, Ismini Donta, Apostolia Vaena, Christos Yapijakis, Eleftherios Vairaktaris Aim: In an effort to assess the role of plasminogen activator inhibitor-1 (PAI-1) in oral squamous cancer development and progression, two different carcinogen treatment protocols were conducted. Materials and methods: Protocol I included mice from a PAI-1 […]